Performance of coated vials for drug storage

The anti-adherent properties of pharmaceutical containers for the storage of protein-based drugs are essential to optimize the cost and reliability of important products such as recombinant proteins and antibodies. Our Consortium will test the efficiency of novel anti-adherent materials as implemented in glass vial prototypes with respect to their performance in long-term storage of drug solutions and during lyophilisation (freeze-drying) protocols routinely used by pharmaceutical companies. Complementary to our experiments of peptide adhesion, in these customer-oriented investigations we will study the adsorption properties of active drug compounds such as tetanus vaccines, immunoglobulins, anti-haemophilic cofactor and recombinant epidermic growth factor proteins.